An Insight into Puzzling Hypervirulent Klebsiella pneumoniae
Hypervirulent Klebsiella pneumoniae (hvKp) is a pathotype that differs sharply from the classical strain that most clinicians know from hosp...
2026
Rods & Rings (AC-23) Pattern: Navigating Challenges
The AC-23 pattern, also known as the “rods and rings” pattern, is a cytoplasmic fluorescence pattern recognized by the International Consens...
Beyond the “Green”: Understanding Viridans Streptococci
Viridans streptococci are a heterogeneous group of alpha-hemolytic, gram-positive cocci arranged in chains and are part of the normal commen...
AC-XX in ANA IIF: When the Pattern Doesn’t Fit the Classification
Antinuclear antibody (ANA) testing is widely used in the evaluation of autoimmune connective tissue diseases, with indirect immunofluorescen...
Beyond Negative Stool Culture: Expanding the Diagnostic Approach
Stool culture remains an important diagnostic investigation in patients with suspected infectious diarrhea, particularly for the detection o...
Optimizing the Basics to Improve Stool Culture Positivity
Stool culture is a fundamental diagnostic tool for identifying bacterial pathogens responsible for gastrointestinal infections. It plays a c...
Dengue Diagnosis: Understanding Bottlenecks & Potential Strategies
Dengue is a mosquito-borne viral disease caused by four antigenically distinct serotypes of the dengue virus (DENV-1 to DENV-4), transmitted...
ANA IIF Methods: Complimentary Rather Than Competitive
The introduction of Automated Indirect Immunofluorescence (ANA IIF) systems has significantly improved the efficiency of autoimmune diagnost...
Trichomonas Infection: Remedying Diagnostic Blind Spots
Trichomoniasis is a common sexually transmitted infection affecting mainly women of reproductive age and is caused by the protozoan Trichomo...
Nuclear Fine Speckled ? Validate Diagnosis Before Sign-Out
The HEp-2 indirect immunofluorescence assay (IFA) remains the most widely used method for detecting autoantibodies associated with systemic ...
Nuclear Fine Speckled ? Validate Diagnosis Before Sign-Out
The HEp-2 indirect immunofluorescence assay (IFA) remains the most widely used method for detecting autoantibodies associated with systemic ...
Smart Mycology: Key Practices for High Impact Results
Fungal infections have traditionally been diagnosed through direct microscopic examination of clinical samples, histopathology and culture. ...
Species Level Fungal Identification: Removes Shadow of Uncertainty
Globally, fungal infections have become far more common and severe. These days, choosing the best antifungal treatment requires quick identi...
ANA IIF: Minimizing Errors to Maximize Diagnostic Impact
The antinuclear antibody (ANA) test is a standard screening assay for detecting antibodies in patient with an autoimmune or ANA associated r...
Nocardia Diagnosis In Lab: Correcting The Oversight
Nocardiosis is a rare bacterial illness that can cause a wide range of symptoms in both immunocompetent and immunocompromised individuals. A...
HSV 1 or 2 Tests: Where Cross Reactions Can Cloud Decisions
Both HSV-1 and HSV-2 cause latent infections in the nervous system that last a lifetime and are incurable. Antiviral drugs can also lessen t...
Auramine Rhodamine O Stain: Salient Rules
Microscopy plays a major role in diagnosing and starting treatment for certain infection. Even though culture is the gold standard for diagn...
